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    Kcnk15 potassium two pore domain channel subfamily K member 15 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 156873, updated on 2-Nov-2024

    Summary

    Official Symbol
    Kcnk15provided by RGD
    Official Full Name
    potassium two pore domain channel subfamily K member 15provided by RGD
    Primary source
    RGD:619733
    See related
    EnsemblRapid:ENSRNOG00000010816 AllianceGenome:RGD:619733
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Orthologous to human KCNK15 (potassium two pore domain channel subfamily K member 15). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 18.8) and Brain (RPKM 18.3) See more
    Orthologs
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    Genomic context

    See Kcnk15 in Genome Data Viewer
    Location:
    3q42
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (172934659..172940877)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (152515237..152521455)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (160231914..160238132)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101781 Neighboring gene uncharacterized LOC134486202 Neighboring gene cellular communication network factor 5 Neighboring gene regulating synaptic membrane exocytosis 4 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables outward rectifier potassium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables potassium ion leak channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    NOT enables voltage-gated monoatomic ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of monoatomic ion channel complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    potassium channel subfamily K member 15
    Names
    TWIK-related acid-sensitive K(+) channel 5
    acid-sensitive potassium channel protein TASK-5
    potassium channel, subfamily K, member 15 (TASK-5)
    potassium channel, two pore domain subfamily K, member 15
    rTASK-5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130813.1NP_570826.1  potassium channel subfamily K member 15 precursor

      See identical proteins and their annotated locations for NP_570826.1

      Status: PROVISIONAL

      Source sequence(s)
      AF467250
      UniProtKB/Swiss-Prot
      Q8R5I0, Q920G1
      UniProtKB/TrEMBL
      A6JX50
      Related
      ENSRNOP00000014411.2, ENSRNOT00000014411.4
      Conserved Domains (1) summary
      pfam07885
      Location:77132
      Ion_trans_2; Ion channel

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      172934659..172940877
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)