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    Sertad1 SERTA domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361526, updated on 2-Nov-2024

    Summary

    Official Symbol
    Sertad1provided by RGD
    Official Full Name
    SERTA domain containing 1provided by RGD
    Primary source
    RGD:1549778
    See related
    EnsemblRapid:ENSRNOG00000024363 AllianceGenome:RGD:1549778
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable transcription coactivator activity. Predicted to act upstream of or within negative regulation of cell growth and positive regulation of transcription by RNA polymerase II. Predicted to be located in sarcoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human SERTAD1 (SERTA domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 145.5), Lung (RPKM 144.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Sertad1 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (91903297..91906565)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (82775692..82778961)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (84293102..84296370)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene biliverdin reductase B Neighboring gene SERTA domain containing 3 Neighboring gene periaxin Neighboring gene transmembrane protein 258, pseudogene 4 Neighboring gene homeodomain interacting protein kinase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC72577

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SERTA domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007735.1NP_001007736.1  SERTA domain-containing protein 1

      See identical proteins and their annotated locations for NP_001007736.1

      Status: PROVISIONAL

      Source sequence(s)
      BC061808
      UniProtKB/TrEMBL
      F7FG80, Q6P771
      Related
      ENSRNOP00000102776.1, ENSRNOT00000145758.1
      Conserved Domains (1) summary
      pfam06031
      Location:4582
      SERTA; SERTA motif

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      91903297..91906565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)