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    Sap30bp SAP30 binding protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360662, updated on 10-Jul-2024

    Summary

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    Official Symbol
    Sap30bpprovided by RGD
    Official Full Name
    SAP30 binding proteinprovided by RGD
    Primary source
    RGD:1565537
    See related
    EnsemblRapid:ENSRNOG00000005482 AllianceGenome:RGD:1565537
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565537
    Summary
    Predicted to be involved in modulation by host of symbiont transcription; positive regulation of histone deacetylation; and response to virus. Predicted to be located in intermediate filament cytoskeleton and nucleoplasm. Predicted to be active in nucleus. Orthologous to human SAP30BP (SAP30 binding protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 75.2), Brain (RPKM 71.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sap30bp in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (101664714..101697430)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (101165777..101198503)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (104483011..104514513)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene RecQ like helicase 5 Neighboring gene small integral membrane protein 5 Neighboring gene small integral membrane protein 6 Neighboring gene ribosomal protein S18-like 1 Neighboring gene integrin subunit beta 4 Neighboring gene galactokinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulation by HSV-1 induced HTRP via acetylation system. Chen J, et al. Virol Sin, 2010 Dec. PMID 21221920, Free PMC Article
    2. HTRP--an immediate-early gene product induced by HSV1 infection in human embryo fibroblasts, is involved in cellular co-repressors. Li JF, et al. J Biochem, 2004 Aug. PMID 15496587
    3. SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. Zhang Y, et al. Mol Cell, 1998 Jun. PMID 9651585
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in modulation by host of symbiont transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to virus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in intermediate filament cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intermediate filament cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    SAP30-binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108305.1 → NP_001101775.1  SAP30-binding protein

      See identical proteins and their annotated locations for NP_001101775.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      B5DFL5, F7FPJ9
      Related
      ENSRNOP00000007362.5, ENSRNOT00000007362.7
      Conserved Domains (1) summary
      pfam07818
      Location:119 → 210
      HCNGP; HCNGP-like protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      101664714..101697430
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086430.2 → XP_038942358.1  SAP30-binding protein isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZR14
      Related
      ENSRNOP00000080761.1, ENSRNOT00000108231.2
      Conserved Domains (1) summary
      pfam07818
      Location:103 → 194
      HCNGP; HCNGP-like protein
    Nucleotide Protein Strain
    Heading Accession and Version

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