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    apc5 anaphase-promoting complex platform subcomplex scaffold TPR subunit Apc5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543355, updated on 22-Jun-2024

    Summary

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    Gene symbol
    apc5
    Gene description
    anaphase-promoting complex platform subcomplex scaffold TPR subunit Apc5
    Locus tag
    SPOM_SPAC959.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAP32A8.01c
    Old locus tag
    SPAC959.09c
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    Genomic context

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    See apc5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003424.3 (3401091..3404142, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS4 Neighboring gene ncRNA Neighboring gene 60S ribosomal protein eL21 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene xylose and arabinose reductase Neighboring gene ubiquitin-protein ligase E3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determinants of robustness in spindle assembly checkpoint signalling. Heinrich S, et al. Nat Cell Biol, 2013 Nov. PMID 24161933
    2. Role of Hcn1 and its phosphorylation in fission yeast anaphase-promoting complex/cyclosome function. Yoon HJ, et al. J Biol Chem, 2006 Oct 27. PMID 16950791
    3. Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1. Ohi MD, et al. Mol Cell, 2007 Dec 14. PMID 18082611, Free PMC Article
    4. The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C). Sczaniecka M, et al. J Biol Chem, 2008 Aug 22. PMID 18556659, Free PMC Article
    5. Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes. Yoon HJ, et al. Curr Biol, 2002 Dec 10. PMID 12477395

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic sister chromatid separation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in positive regulation of mitotic metaphase/anaphase transition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein K11-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of anaphase-promoting complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus EXP
    Inferred from Experiment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    anaphase-promoting complex platform subcomplex scaffold TPR subunit Apc5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3401091..3404142 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356113.2 → NP_001342967.1  anaphase-promoting complex platform subcomplex scaffold TPR subunit Apc5 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9C1X6, Q9P4W7
      Conserved Domains (2) summary
      sd00016
      Location:258 → 291
      Apc5; TPR repeat [structural motif]
      pfam12862
      Location:263 → 353
      ANAPC5; Anaphase-promoting complex subunit 5
    Nucleotide Protein
    Heading Accession and Version

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