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    VBA2 Vba2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852596, updated on 29-Jun-2024

    Summary

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    Gene symbol
    VBA2
    Gene description
    Vba2p
    Primary source
    FungiDB:YBR293W
    Locus tag
    YBR293W
    See related
    SGD:S000000497; AllianceGenome:SGD:S000000497; VEuPathDB:YBR293W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables basic amino acid transmembrane transporter activity. Involved in basic amino acid transport and transmembrane transport. Located in fungal-type vacuole membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See VBA2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (787006..788430)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Ctp1p Neighboring gene uncharacterized protein Neighboring gene sulfate permease Neighboring gene cation-transporting P-type ATPase PCA1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of fnx1, a fission yeast multidrug resistance protein, in the transition of cells to a quiescent G0 state. Dimitrov K, et al. Mol Cell Biol, 1998 Sep. PMID 9710608, Free PMC Article
    2. Vba4p, a vacuolar membrane protein, is involved in the drug resistance and vacuolar morphology of Saccharomyces cerevisiae. Kawano-Kawada M, et al. Biosci Biotechnol Biochem, 2016. PMID 26325352
    3. A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. Shimazu M, et al. J Biol Chem, 2005 Feb 11. PMID 15572352
    4. Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae. Aye M, et al. Genetics, 2004 Nov. PMID 15579677, Free PMC Article
    5. Systems analysis of the genetic interaction network of yeast molecular chaperones. Rizzolo K, et al. Mol Omics, 2018 Apr 16. PMID 29659649

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables basic amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables basic amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables basic amino acid transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in basic amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in basic amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in basic amino acid transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in fungal-type vacuole membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Vba2p
    NP_009852.3
    • Permease of basic amino acids in the vacuolar membrane

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      787006..788430
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178641.3 → NP_009852.3  TPA: Vba2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009852.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQT7, P38358
      UniProtKB/TrEMBL
      A0A8H4BUA6, C7GMU0, D3UF40, N1P8Q0
      Conserved Domains (2) summary
      pfam06609
      Location:107 → 249
      TRI12; Fungal trichothecene efflux pump (TRI12)
      cl28910
      Location:1 → 384
      MFS; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38358.1

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