U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CASC18 cancer susceptibility 18 [ Homo sapiens (human) ]

    Gene ID: 101929110, updated on 17-Sep-2024

    Summary

    Official Symbol
    CASC18provided by HGNC
    Official Full Name
    cancer susceptibility 18provided by HGNC
    Primary source
    HGNC:HGNC:49463
    See related
    Ensembl:ENSG00000257859 AllianceGenome:HGNC:49463
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CASC18 in Genome Data Viewer
    Location:
    12q23.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (105704203..105744063)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (105667013..105706864)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (106097981..106137841)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369958 Neighboring gene Sharpr-MPRA regulatory region 9585 Neighboring gene uncharacterized LOC124903006 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:105955477-105956256 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:106022357-106023010 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr12:106091383-106092582 Neighboring gene uncharacterized LOC105369959 Neighboring gene uncharacterized LOC107984435 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr12:106133756-106134367 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr12:106134368-106134978 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:106138325-106138868 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:106170114-106170679 Neighboring gene uncharacterized LOC105369960 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6943 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6944 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:106254933-106255434 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:106289604-106290350 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:106290351-106291097 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr12:106291098-106291844 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr12:106328523-106329722 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr12:106348645-106349844 Neighboring gene ST13, Hsp70 interacting protein pseudogene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Phenotypes

    EBI GWAS Catalog

    Description
    APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Other Names

    • cancer susceptibility 18 (non-protein coding)
    • cancer susceptibility candidate 18 (non-protein coding)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_110108.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two alternate exons compared to variant 1.
      Source sequence(s)
      AB849958
      Related
      ENST00000548557.1
    2. NR_110109.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AB849958, AB849961
    3. NR_110110.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate first exon and lacks two alternate exons compared to variant 1.
      Source sequence(s)
      AB849963
    4. NR_110111.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate first exon and lacks three alternate exons compared to variant 1.
      Source sequence(s)
      AC079851, AC084356

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      105704203..105744063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      105667013..105706864
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)