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    RNP1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850680, updated on 22-Aug-2024

    Summary

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    Official Symbol
    RNP1
    Primary source
    FungiDB:YLL046C
    Locus tag
    YLL046C
    See related
    SGD:S000003969; AllianceGenome:SGD:S000003969; VEuPathDB:YLL046C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable RNA binding activity. Involved in ribosome biogenesis. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (46714..47463, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Ldb18p Neighboring gene bile acid-transporting ATPase YBT1 Neighboring gene ribosomal 60S subunit protein L8B Neighboring gene Fps1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A protein containing conserved RNA-recognition motifs is associated with ribosomal subunits in Saccharomyces cerevisiae. Ripmaster TL, et al. Nucleic Acids Res, 1993 Jul 11. PMID 8341595, Free PMC Article
    2. RNP1, a new ribonucleoprotein gene of the yeast Saccharomyces cerevisiae. Cusick ME. Nucleic Acids Res, 1994 Mar 11. PMID 8139928, Free PMC Article
    3. Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Reid RJ, et al. Genome Res, 2011 Mar. PMID 21173034, Free PMC Article
    4. Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. León Ortiz AM, et al. DNA Repair (Amst), 2011 May 5. PMID 21459050, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome XII. Johnston M, et al. Nature, 1997 May 29. PMID 9169871, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosome biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Rnp1p
    NP_013054.1
    • Ribonucleoprotein that contains two RNA recognition motifs (RRM); RNP1 has a paralog, SBP1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      46714..47463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181866.1 → NP_013054.1  TPA: Rnp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013054.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXW1, P32385
      UniProtKB/TrEMBL
      A7A0L3, B3LTC9, B5VMQ4, C7GNE8, C8ZCS8, G2WIF2, N1NY51
      Conserved Domains (2) summary
      smart00360
      Location:36 → 109
      RRM; RNA recognition motif
      COG0724
      Location:22 → 224
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32385.2

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