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    Polr3d RNA polymerase III subunit D [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306012, updated on 17-Aug-2024

    Summary

    Official Symbol
    Polr3dprovided by RGD
    Official Full Name
    RNA polymerase III subunit Dprovided by RGD
    Primary source
    RGD:1311816
    See related
    EnsemblRapid:ENSRNOG00000010028 AllianceGenome:RGD:1311816
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in positive regulation of innate immune response and positive regulation of interferon-beta production. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of RNA polymerase III complex. Orthologous to human POLR3D (RNA polymerase III subunit D). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 179.7), Heart (RPKM 105.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    Location:
    15p11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (51921283..51925952, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (45511587..45516256, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (52129471..52134140, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene piwi-like RNA-mediated gene silencing 2 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene transfer RNA proline (anticodon AGG) 23 Neighboring gene microRNA 320a Neighboring gene uncharacterized LOC120097030 Neighboring gene phytanoyl-CoA 2-hydroxylase interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC116334

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in positive regulation of innate immune response ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of interferon-beta production ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase III complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerase III subunit RPC4
    Names
    polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
    polymerase (RNA) III subunit D
    NP_001026823.1
    XP_006252334.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031653.1NP_001026823.1  DNA-directed RNA polymerase III subunit RPC4

      See identical proteins and their annotated locations for NP_001026823.1

      Status: PROVISIONAL

      Source sequence(s)
      BC099167
      UniProtKB/TrEMBL
      F7EKD9, Q4FZS9
      Related
      ENSRNOP00000013390.4, ENSRNOT00000013390.6
      Conserved Domains (1) summary
      pfam05132
      Location:263389
      RNA_pol_Rpc4; RNA polymerase III RPC4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      51921283..51925952 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006252272.5XP_006252334.1  DNA-directed RNA polymerase III subunit RPC4 isoform X1

      See identical proteins and their annotated locations for XP_006252334.1

      UniProtKB/TrEMBL
      F7EKD9, Q4FZS9
      Conserved Domains (1) summary
      pfam05132
      Location:263389
      RNA_pol_Rpc4; RNA polymerase III RPC4