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    Nol4 nucleolar protein 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307553, updated on 17-Aug-2024

    Summary

    Official Symbol
    Nol4provided by RGD
    Official Full Name
    nucleolar protein 4provided by RGD
    Primary source
    RGD:1310663
    See related
    EnsemblRapid:ENSRNOG00000014775 AllianceGenome:RGD:1310663
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in nucleolus. Orthologous to human NOL4 (nucleolar protein 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 83.6), Testes (RPKM 22.5) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Nol4 in Genome Data Viewer
    Location:
    18p12
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (14207303..14569697, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (13932499..14294873, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (13658260..14016713, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene ASXL transcriptional regulator 3 Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC120098257 Neighboring gene cytochrome b5 type A, pseudogene 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene dystrobrevin, alpha Neighboring gene uncharacterized LOC120098123

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107401.1NP_001100871.1  nucleolar protein 4 isoform 1

      See identical proteins and their annotated locations for NP_001100871.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473974
      UniProtKB/TrEMBL
      A6J2I2
      Related
      ENSRNOP00000107260.1, ENSRNOT00000131803.1
    2. NM_001415694.1NP_001402623.1  nucleolar protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      D4A3P4
      Related
      ENSRNOP00000038969.4, ENSRNOT00000041125.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      14207303..14569697 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039096914.2XP_038952842.1  nucleolar protein 4 isoform X3

      Related
      ENSRNOP00000104273.1, ENSRNOT00000154299.1
      Conserved Domains (2) summary
      pfam17921
      Location:110164
      Integrase_H2C2; Integrase zinc binding domain
      NF033845
      Location:208414
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    2. XM_039096918.2XP_038952846.1  nucleolar protein 4 isoform X8

      Conserved Domains (1) summary
      NF033845
      Location:229400
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    3. XM_017600973.3XP_017456462.1  nucleolar protein 4 isoform X1

    4. XM_063277444.1XP_063133514.1  nucleolar protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8I6ADW2
      Related
      ENSRNOP00000090479.1, ENSRNOT00000103441.2
    5. XM_039096915.2XP_038952843.1  nucleolar protein 4 isoform X4

      Conserved Domains (2) summary
      pfam17921
      Location:1550
      Integrase_H2C2; Integrase zinc binding domain
      NF033845
      Location:94265
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    6. XM_017600974.3XP_017456463.1  nucleolar protein 4 isoform X5

    7. XM_017600975.3XP_017456464.1  nucleolar protein 4 isoform X6

    8. XM_039096917.2XP_038952845.1  nucleolar protein 4 isoform X7