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    Tmem37 transmembrane protein 37 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 245953, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Tmem37provided by RGD
    Official Full Name
    transmembrane protein 37provided by RGD
    Primary source
    RGD:628689
    See related
    EnsemblRapid:ENSRNOG00000047714 AllianceGenome:RGD:628689
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pr; Pr1
    Summary
    Predicted to enable calcium channel activity and voltage-gated ion channel activity. Predicted to be involved in calcium ion transmembrane transport and regulation of ion transmembrane transport. Predicted to be integral component of membrane. Orthologous to human TMEM37 (transmembrane protein 37). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 207.1), Liver (RPKM 173.3) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    13q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (33737096..33743602, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (31184322..31191477, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (36094665..36101443, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 221 Neighboring gene uncharacterized LOC134481481 Neighboring gene secretin receptor Neighboring gene similar to chromosome 2 open reading frame 76 Neighboring gene diazepam binding inhibitor Neighboring gene STEAP3 metalloreductase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Calcium channel gamma subunits provide insights into the evolution of this gene family. Chu PJ, et al. Gene, 2001 Dec 12. PMID 11738816

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables voltage-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of monoatomic ion channel complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    voltage-dependent calcium channel gamma-like subunit
    Names
    neuronal voltage-gated calcium channel gamma-like subunit
    protein distantly related to to the gamma subunit family
    voltage-dependent calcium channel gamma subunit-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139095.2 → NP_620795.2  voltage-dependent calcium channel gamma-like subunit

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/TrEMBL
      A6K7Y6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      33737096..33743602 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008769424.4 → XP_008767646.1  voltage-dependent calcium channel gamma-like subunit isoform X1

      UniProtKB/TrEMBL
      A6K7Y6, M0RCX9
      Related
      ENSRNOP00000067466.2, ENSRNOT00000074471.4
      Conserved Domains (1) summary
      pfam15108
      Location:19 → 199
      TMEM37; Voltage-dependent calcium channel gamma-like subunit protein family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VHW1.1 GenPept UniProtKB/Swiss-Prot:Q8VHW1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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