Csn1s1 casein alpha s1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Csn1s1provided by RGD
Official Full Name: casein alpha s1provided by RGD
Primary source: RGD:2430
See related: AllianceGenome:RGD:2430
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Casa; Csn1; Csna
Summary: Predicted to be involved in response to dehydroepiandrosterone; response to estradiol; and response to steroid hormone. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human CSN1S1 (casein alpha s1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 48.0) See more
Orthologs: human mouse all
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Genomic context

Location:: 14p21

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (20622858..20638849, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (20343620..20359614, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (21993450..22009308, complement)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

present in a membrane-associated form in the endoplasmic reticulum and in more distal compartments of the secretory pathway of mammary epithelial cells
Title: AlphaS1-casein, which is essential for efficient ER-to-Golgi casein transport, is also present in a tightly membrane-associated form.

Submit: New GeneRIF Correction

General gene information

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Markers

D14Arb18 (e-PCR)
- UniSTS:240151

D14Wox14 (e-PCR)
- UniSTS:118051

RH133429 (e-PCR)
- UniSTS:216712

D14Got29 (e-PCR)
- UniSTS:113829

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in response to 11-deoxycorticosterone	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to dehydroepiandrosterone	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to estradiol	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to progesterone	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in extracellular region	ISO Inferred from Sequence Orthology more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: alpha-S1-casein

Names: Casein, alpha; alpha-casein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.