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    Saxo1 stabilizer of axonemal microtubules 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679802, updated on 5-Mar-2024

    Summary

    Official Symbol
    Saxo1provided by RGD
    Official Full Name
    stabilizer of axonemal microtubules 1provided by RGD
    Primary source
    RGD:1583685
    See related
    Ensembl:ENSRNOG00000048197 AllianceGenome:RGD:1583685
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam154a
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including cold acclimation; positive regulation of cilium assembly; and protein stabilization. Predicted to be located in motile cilium. Predicted to be active in microtubule cytoskeleton and sperm flagellum. Orthologous to human SAXO1 (stabilizer of axonemal microtubules 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 65.6) See more
    Orthologs
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    Genomic context

    See Saxo1 in Genome Data Viewer
    Location:
    5q31
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (105982949..106139298, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (100937134..101093308, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (104771081..104921001, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene phosphoglycerate mutase 1, pseudogene 6 Neighboring gene SH3 domain containing GRB2 like 2, endophilin A1 Neighboring gene ADAMTS-like 1 Neighboring gene small Cajal body-specific RNA 8 Neighboring gene Ras-related GTP binding A Neighboring gene HAUS augmin like complex subunit 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to cold ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cold acclimation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in axonemal microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in axonemal microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in motile cilium ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in sperm flagellum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    stabilizer of axonemal microtubules 1
    Names
    family with sequence similarity 154, member A
    rCG55202-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      105982949..106139298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006238373.5XP_006238435.1  stabilizer of axonemal microtubules 1

      See identical proteins and their annotated locations for XP_006238435.1

      UniProtKB/TrEMBL
      A6J863, A6J864, M0R6K6
      Related
      ENSRNOP00000065058.2
      Conserved Domains (1) summary
      pfam05217
      Location:5218
      STOP; STOP protein