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    ERP3 Erp3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851544, updated on 29-Jun-2024

    Summary

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    Gene symbol
    ERP3
    Gene description
    Erp3p
    Primary source
    FungiDB:YDL018C
    Locus tag
    YDL018C
    See related
    SGD:S000002176; AllianceGenome:SGD:S000002176; VEuPathDB:YDL018C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in several processes, including Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and protein retention in ER lumen. Located in endoplasmic reticulum. Orthologous to several human genes including TMED1 (transmembrane p24 trafficking protein 1) and TMED5 (transmembrane p24 trafficking protein 5). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ERP3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (422833..423510, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene stress-regulated transcription factor RPN4 Neighboring gene oxysterol-binding protein related protein OSH2 Neighboring gene serine/threonine protein kinase CDC7 Neighboring gene trans-2-enoyl-CoA reductase (NADPH) TSC13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae. Springer S, et al. Proc Natl Acad Sci U S A, 2000 Apr 11. PMID 10737764, Free PMC Article
    2. Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. Marzioch M, et al. Mol Biol Cell, 1999 Jun. PMID 10359606, Free PMC Article
    3. Isoform-selective oligomer formation of Saccharomyces cerevisiae p24 family proteins. Hirata R, et al. J Biol Chem, 2013 Dec 27. PMID 24217251, Free PMC Article
    4. Identification of aluminium transport-related genes via genome-wide phenotypic screening of Saccharomyces cerevisiae. Tun NM, et al. Metallomics, 2014 Aug. PMID 24926745
    5. Vps39 Interacts with Tom40 to Establish One of Two Functionally Distinct Vacuole-Mitochondria Contact Sites. González Montoro A, et al. Dev Cell, 2018 Jun 4. PMID 29870720

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables cargo receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein retention in ER lumen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Erp3p
    NP_010266.1
    • Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      422833..423510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180077.1 → NP_010266.1  TPA: Erp3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010266.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRX2, Q12403
      UniProtKB/TrEMBL
      A0A8H8UMQ6, C7GW61, C8Z4Q1
      Conserved Domains (1) summary
      pfam01105
      Location:23 → 218
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12403.1

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