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    RPL13A ribosomal 60S subunit protein L13A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851477, updated on 3-Nov-2024

    Summary

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    Official Symbol
    RPL13A
    Official Full Name
    ribosomal 60S subunit protein L13A
    Primary source
    SGD:S000002240
    Locus tag
    YDL082W
    See related
    AllianceGenome:SGD:S000002240; FungiDB:YDL082W; VEuPathDB:YDL082W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL13 (ribosomal protein L13). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See RPL13A in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_001136.10 (308424..309388)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase SUB2 Neighboring gene ribosomal 40S subunit protein S16B Neighboring gene ribosomal protein P1A Neighboring gene branched-chain-2-oxoacid decarboxylase THI3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Natural Variation in Lifespans of Single Yeast Cells Is Related to Variation in Cell Size, Ribosomal Protein, and Division Time. Janssens GE, et al. PLoS One, 2016. PMID 27907085, Free PMC Article
    2. Disruption of six Saccharomyces cerevisiae genes from chromosome IV and basic phenotypic analysis of deletion mutants. López MC, et al. Yeast, 1998 Sep 30. PMID 9791891
    3. Transcription factor substitution during the evolution of fungal ribosome regulation. Hogues H, et al. Mol Cell, 2008 Mar 14. PMID 18342603, Free PMC Article
    4. Tolerance to acetic acid is improved by mutations of the TATA-binding protein gene. An J, et al. Environ Microbiol, 2015 Mar. PMID 24761971
    5. Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase. Panasenko OO, et al. Mol Microbiol, 2012 Feb. PMID 22243599

    See all (103) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L13A
    NP_010201.1
    • Ribosomal 60S subunit protein L13A; not essential for viability; homologous to mammalian ribosomal protein L13, no bacterial homolog; RPL13A has a paralog, RPL13B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      308424..309388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180141.1 → NP_010201.1  TPA: ribosomal 60S subunit protein L13A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010201.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRR7, Q12690
      UniProtKB/TrEMBL
      A6ZXP6, B3LGX6, C8Z6M2, N1P7P8
      Conserved Domains (1) summary
      pfam01294
      Location:8 → 175
      Ribosomal_L13e; Ribosomal protein L13e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12690.1

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