ASN2 asparagine synthase (glutamine-hydrolyzing) 2 [Saccharomyces cerevisiae S288C] - Gene

Summary

Go to the top of the page Help

Official Symbol: ASN2
Official Full Name: asparagine synthase (glutamine-hydrolyzing) 2
Primary source: SGD:S000003356
Locus tag: YGR124W
See related: AllianceGenome:SGD:S000003356; FungiDB:YGR124W; VEuPathDB:YGR124W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables asparagine synthase (glutamine-hydrolyzing) activity. Involved in asparagine biosynthetic process. Located in cytoplasm. Orthologous to human ASNS (asparagine synthetase (glutamine-hydrolyzing)). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See ASN2 in Genome Data Viewer

Location:: chromosome: VII

Exon count:: 1

Sequence:: Chromosome: VII; NC_001139.9 (739944..741662)

Chromosome VII - NC_001139.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Nuclear targeted Saccharomyces cerevisiae asparagine synthetases associate with the mitotic spindle regardless of their enzymatic activity.
Title: Nuclear targeted Saccharomyces cerevisiae asparagine synthetases associate with the mitotic spindle regardless of their enzymatic activity.

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables asparagine synthase (glutamine-hydrolyzing) activity	IBA Inferred from Biological aspect of Ancestor more info
enables asparagine synthase (glutamine-hydrolyzing) activity	IDA Inferred from Direct Assay more info	PubMed
enables asparagine synthase (glutamine-hydrolyzing) activity	IEA Inferred from Electronic Annotation more info
enables ligase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-asparagine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in asparagine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in asparagine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in asparagine biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in glutamine metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: asparagine synthase (glutamine-hydrolyzing) 2

NP_011640.1

EC 6.3.5.4

Asparagine synthetase; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway; ASN2 has a paralog, ASN1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001139.9 Reference assembly

Range

739944..741662

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001181253.1 → NP_011640.1 TPA: asparagine synthase (glutamine-hydrolyzing) 2 [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_011640.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VUQ6, E9P8Y0, P49090

UniProtKB/TrEMBL

A6ZUD8, B3LIA4, C7GUH1, C8Z917, G2WEK6, N1P2B6

Conserved Domains (1) summary

PRK09431
Location:1 → 561

asnB; asparagine synthetase B; Provisional