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    REC104 Rec104p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856562, updated on 17-May-2024

    Summary

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    Gene symbol
    REC104
    Gene description
    Rec104p
    Primary source
    FungiDB:YHR157W
    Locus tag
    YHR157W
    See related
    SGD:S000001200; AllianceGenome:SGD:S000001200; VEuPathDB:YHR157W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in reciprocal meiotic recombination. Located in condensed nuclear chromosome. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See REC104 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (412907..413455)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U5 snRNP complex subunit LIN1 Neighboring gene Kel1p Neighboring gene Tda11p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of REC104, a gene required for early meiotic recombination in the yeast Saccharomyces cerevisiae. Galbraith AM, et al. Dev Genet, 1992. PMID 1304422
    2. Support for a meiotic recombination initiation complex: interactions among Rec102p, Rec104p, and Spo11p. Jiao K, et al. Mol Cell Biol, 2003 Aug. PMID 12897161, Free PMC Article
    3. Recombination and the progression of meiosis in Saccharomyces cerevisiae. Galbraith AM, et al. Genetics, 1997 Jun. PMID 9177999, Free PMC Article
    4. A conditional allele of the Saccharomyces cerevisiae HOP1 gene is suppressed by overexpression of two other meiosis-specific genes: RED1 and REC104. Hollingsworth NM, et al. Genetics, 1993 Apr. PMID 8462842, Free PMC Article
    5. Insertional mutations in the yeast HOP1 gene: evidence for multimeric assembly in meiosis. Friedman DB, et al. Genetics, 1994 Feb. PMID 8150275, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in meiotic DNA double-strand break formation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic DNA double-strand break formation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in reciprocal meiotic recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in condensed nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Rec104p
    NP_012027.1
    • Protein involved in early stages of meiotic recombination; required for meiotic crossing over; forms a complex with Rec102p and Spo11p necessary during the initiation of recombination

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      412907..413455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179288.1 → NP_012027.1  TPA: Rec104p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012027.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLA6, P33323
      UniProtKB/TrEMBL
      A0A8H4C279, A6ZT65, G2WFN0, N1P2W9
      Conserved Domains (1) summary
      pfam17378
      Location:1 → 182
      REC104; Meiotic recombination protein REC104
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P33323.1

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