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    COX7 cytochrome c oxidase subunit VII [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855298, updated on 18-Sep-2024

    Summary

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    Official Symbol
    COX7
    Official Full Name
    cytochrome c oxidase subunit VII
    Primary source
    SGD:S000004869
    Locus tag
    YMR256C
    See related
    AllianceGenome:SGD:S000004869; FungiDB:YMR256C; VEuPathDB:YMR256C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Contributes to cytochrome-c oxidase activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Part of mitochondrial respiratory chain complex IV. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See COX7 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (778945..779127, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gfd1p Neighboring gene Pet111p Neighboring gene Roy1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast cytochrome c oxidase subunit VII is essential for assembly of an active enzyme. Cloning, sequencing, and characterization of the nuclear-encoded gene. Aggeler R, et al. J Biol Chem, 1990 Sep 25. PMID 2168889
    2. Nucleotide sequence of the gene encoding cytochrome c oxidase subunit VII from Saccharomyces cerevisiae. Calder KM, et al. Nucleic Acids Res, 1990 Mar 25. PMID 2158084, Free PMC Article
    3. Monitoring yeast mitochondria with peroxiredoxin-based redox probes: the influence of oxygen and glucose availability. Pastor-Flores D, et al. Interface Focus, 2017 Apr 6. PMID 28382205, Free PMC Article
    4. Study of a region on yeast chromosome XIII that complements pet G199 mutants (COX7) and carries a new non-essential gene. Nobrega MP, et al. Braz J Med Biol Res, 1998 Mar. PMID 9698782
    5. Deletion of the COX7 gene in Saccharomyces cerevisiae reveals a role for cytochrome c oxidase subunit VII in assembly of remaining subunits. Calder KM, et al. Mol Microbiol, 1991 Jul. PMID 1658541

    See all (67) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to cytochrome-c oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, cytochrome c to oxygen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in oxidative phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IV IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome c oxidase subunit VII
    NP_013983.1
    • Subunit VII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      778945..779127 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182763.1 → NP_013983.1  TPA: cytochrome c oxidase subunit VII [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013983.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W082, P10174
      UniProtKB/TrEMBL
      A6ZMX1, B3LME4, C7GR96, C8ZFC2, G2WKW4, N1NZ38
      Conserved Domains (1) summary
      pfam02238
      Location:3 → 54
      COX7a; Cytochrome c oxidase subunit VII
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P10174.3

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