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    PNS1 Pns1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854332, updated on 2-Nov-2024

    Summary

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    Official Symbol
    PNS1
    Official Full Name
    Pns1p
    Primary source
    SGD:S000005687
    Locus tag
    YOR161C
    See related
    AllianceGenome:SGD:S000005687; FungiDB:YOR161C; VEuPathDB:YOR161C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in plasma membrane. Orthologous to human SLC44A5 (solute carrier family 44 member 5). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See PNS1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (636939..638558, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene mRNA splicing protein SME1 Neighboring gene Mtr10p Neighboring gene uncharacterized protein Neighboring gene Yrr1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reexamining the role of choline transporter-like (Ctlp) proteins in choline transport. Zufferey R, et al. Neurochem Res, 2004 Feb. PMID 15002745
    2. Functional analysis of six genes from chromosomes XIV and XV of Saccharomyces cerevisiae reveals YOR145c as an essential gene and YNL059c/ARP5 as a strain-dependent essential gene encoding nuclear proteins. Grava S, et al. Yeast, 2000 Aug. PMID 10923024
    3. The plasma membrane proteome of Saccharomyces cerevisiae and its response to the antifungal calcofluor. Delom F, et al. Proteomics, 2006 May. PMID 16622836
    4. Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners. O'Connor HF, et al. EMBO Rep, 2015 Dec. PMID 26508657, Free PMC Article
    5. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pns1p
    NP_014804.3
    • hypothetical protein; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      636939..638558 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183580.3 → NP_014804.3  TPA: Pns1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014804.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2L8, Q12412, Q6B2U3
      UniProtKB/TrEMBL
      A6ZP05, B3LJJ3, C7GN64, C8ZGR9, N1NX20
      Conserved Domains (1) summary
      pfam04515
      Location:187 → 510
      Choline_transpo; Plasma-membrane choline transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12412.1

    Gene LinkOut

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