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    RRP36 rRNA-processing protein RRP36 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854461, updated on 17-May-2024

    Summary

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    Gene symbol
    RRP36
    Gene description
    rRNA-processing protein RRP36
    Primary source
    FungiDB:YOR287C
    Locus tag
    YOR287C
    See related
    SGD:S000005813; AllianceGenome:SGD:S000005813; VEuPathDB:YOR287C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in cleavage involved in rRNA processing and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. Part of 90S preribosome. Orthologous to human RRP36 (ribosomal RNA processing 36). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RRP36 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (850937..851839, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene thiosulfate sulfurtransferase RDL1 Neighboring gene thiosulfate sulfurtransferase RDL2 Neighboring gene protein disulfide isomerase MPD1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Synergistic defects in pre-rRNA processing from mutations in the U3-specific protein Rrp9 and U3 snoRNA. Clerget G, et al. Nucleic Acids Res, 2020 Apr 17. PMID 31996908, Free PMC Article
    2. Evolutionarily conserved function of RRP36 in early cleavages of the pre-rRNA and production of the 40S ribosomal subunit. Gérus M, et al. Mol Cell Biol, 2010 Mar. PMID 20038530, Free PMC Article
    3. The budding yeast rRNA and ribosome biosynthesis (RRB) regulon contains over 200 genes. Wade CH, et al. Yeast, 2006 Mar. PMID 16544271
    4. A panoramic view of yeast noncoding RNA processing. Peng WT, et al. Cell, 2003 Jun 27. PMID 12837249
    5. The SSU processome interactome in Saccharomyces cerevisiae reveals novel protein subcomplexes. Vincent NG, et al. RNA, 2018 Jan. PMID 29054886, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ribosomal small subunit biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of 90S preribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    rRNA-processing protein RRP36
    NP_014930.1
    • Component of 90S preribosomes; involved in early cleavages of the 35S pre-rRNA and in production of the 40S ribosomal subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      850937..851839 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183706.1 → NP_014930.1  TPA: rRNA-processing protein RRP36 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014930.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2Y5, Q12481
      UniProtKB/TrEMBL
      A0A8H4BV66, G2WNF3, N1P3N4
      Conserved Domains (2) summary
      pfam06102
      Location:120 → 285
      RRP36; rRNA biogenesis protein RRP36
      cl27223
      Location:6 → 142
      CBF; CBF/Mak21 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12481.1

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