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    RRG8 Rrg8p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856232, updated on 17-May-2024

    Summary

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    Gene symbol
    RRG8
    Gene description
    Rrg8p
    Primary source
    FungiDB:YPR116W
    Locus tag
    YPR116W
    See related
    SGD:S000006320; AllianceGenome:SGD:S000006320; VEuPathDB:YPR116W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MTA1
    Summary
    Involved in mitochondrial genome maintenance and mitochondrial tRNA 5'-end processing. Located in matrix side of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RRG8 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (758648..759481)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Rgc1p Neighboring gene Hob2p Neighboring gene S-methyl-5-thioribose-1-phosphate isomerase MRI1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sulforaphane alters the acidification of the yeast vacuole. Wilcox A, et al. Microb Cell, 2020 Mar 20. PMID 32391394, Free PMC Article
    2. 5' processing of Saccharomyces cerevisiae mitochondrial tRNAs requires expression of multiple genes. Guedes-Monteiro RF, et al. Biochim Biophys Acta Mol Cell Res, 2019 May. PMID 30759361
    3. Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. Herst PM, et al. FEMS Yeast Res, 2008 Sep. PMID 18657191
    4. Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Merz S, et al. Genome Biol, 2009. PMID 19751518, Free PMC Article
    5. Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning. Peng Y, et al. Mol Biol Cell, 2015 Jul 1. PMID 25971801, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial genome maintenance IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial genome maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial tRNA 5'-end processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in matrix side of mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Rrg8p
    NP_015441.1
    • hypothetical protein; required for efficient 5' processing of mitochondrial tRNAs, for respiratory growth and mitochondrial genome maintenance; null mutation results in a decrease in plasma membrane electron transport; localizes to the matrix side of the inner mitochondrial membrane

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      758648..759481
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184213.1 → NP_015441.1  TPA: Rrg8p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015441.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZWZ7, D6W4B5, Q06109
      UniProtKB/TrEMBL
      A0A8H4F8F1, N1NXQ8
      Conserved Domains (1) summary
      pfam17068
      Location:8 → 273
      RRG8; Required for respiratory growth protein 8 mitochondrial
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06109.1

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