Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Taf1cprovided by RGD
Official Full Name: TATA-box binding protein associated factor, RNA polymerase 1 subunit Cprovided by RGD
Primary source: RGD:1305658
See related: EnsemblRapid:ENSRNOG00000015632 AllianceGenome:RGD:1305658
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of RNA polymerase transcription factor SL1 complex. Predicted to be active in fibrillar center. Orthologous to human TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Thymus (RPKM 35.0), Testes (RPKM 31.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q12

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (64561079..64567599, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (47652451..47658971, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (52246061..52252642, complement)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI145291 (e-PCR)
- UniSTS:261127

RH134909 (e-PCR)
- UniSTS:218187

BE115013 (e-PCR)
- UniSTS:261301

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA polymerase I core promoter sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase I core promoter sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase I general transcription initiation factor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in RNA polymerase I preinitiation complex assembly	IEA Inferred from Electronic Annotation more info
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
part_of RNA polymerase transcription factor SL1 complex	ISO Inferred from Sequence Orthology more info
is_active_in fibrillar center	IBA Inferred from Biological aspect of Ancestor more info
located_in fibrillar center	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: TATA box-binding protein-associated factor, RNA polymerase I, subunit C

Names: TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C; TATA box-binding protein-associated factor 1C; TBP-associated factor 1C; transcription initiation factor SL1/TIF-IB subunit C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001014155.1 → NP_001014177.1 TATA box-binding protein-associated factor, RNA polymerase I, subunit C

See identical proteins and their annotated locations for NP_001014177.1

Status: PROVISIONAL

Source sequence(s)

BC061804

UniProtKB/Swiss-Prot

Q6P773

Related

ENSRNOP00000020990.4, ENSRNOT00000020990.6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086037.1 Reference GRCr8

Range

64561079..64567599 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063278146.1 → XP_063134216.1 TATA box-binding protein-associated factor, RNA polymerase I, subunit C isoform X1
XM_039097872.2 → XP_038953800.1 TATA box-binding protein-associated factor, RNA polymerase I, subunit C isoform X1
XM_039097873.2 → XP_038953801.1 TATA box-binding protein-associated factor, RNA polymerase I, subunit C isoform X1
XM_063278147.1 → XP_063134217.1 TATA box-binding protein-associated factor, RNA polymerase I, subunit C isoform X1