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    Psmd5 proteasome 26S subunit, non-ATPase 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296651, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Psmd5provided by RGD
    Official Full Name
    proteasome 26S subunit, non-ATPase 5provided by RGD
    Primary source
    RGD:1308434
    See related
    Ensembl:ENSRNOG00000018809 AllianceGenome:RGD:1308434
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in proteasome regulatory particle assembly. Predicted to be part of proteasome accessory complex. Orthologous to human PSMD5 (proteasome 26S subunit, non-ATPase 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 199.6), Liver (RPKM 152.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Psmd5 in Genome Data Viewer
    Location:
    3p11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (38531206..38552085, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (18133715..18151000, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (13916199..13937031, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene F-box and WD repeat domain containing 2 Neighboring gene beta-1,3-galactosyltransferase 9 Neighboring gene cutA divalent cation tolerance homolog-like Neighboring gene PHD finger protein 19 Neighboring gene RNA, U6 small nuclear 1256 Neighboring gene TNF receptor-associated factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones. Kaneko T, et al. Cell, 2009 May 29. PMID 19490896
    2. Chaperone-mediated pathway of proteasome regulatory particle assembly. Roelofs J, et al. Nature, 2009 Jun 11. PMID 19412159, Free PMC Article
    3. Mapping the murine cardiac 26S proteasome complexes. Gomes AV, et al. Circ Res, 2006 Aug 18. PMID 16857966
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in proteasome regulatory particle assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of proteasome accessory complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of proteasome regulatory particle, base subcomplex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    26S proteasome non-ATPase regulatory subunit 5
    Names
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106569.2 → NP_001100039.2  26S proteasome non-ATPase regulatory subunit 5

      See identical proteins and their annotated locations for NP_001100039.2

      Status: VALIDATED

      Source sequence(s)
      BC166850, JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I5ZMJ6, A6JUD4, G3V8G2
      Related
      ENSRNOP00000025433.4, ENSRNOT00000025433.7
      Conserved Domains (1) summary
      pfam10508
      Location:1 → 504
      Proteasom_PSMB; Proteasome non-ATPase 26S subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      38531206..38552085 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283521.1 → XP_063139591.1  26S proteasome non-ATPase regulatory subunit 5 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMJ6, A6JUD4, G3V8G2

    2. XM_063283520.1 → XP_063139590.1  26S proteasome non-ATPase regulatory subunit 5 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMJ6, A6JUD4, G3V8G2
    Nucleotide Protein Strain
    Heading Accession and Version

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