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    mam4 protein-S isoprenylcysteine O-methyltransferase Mam4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542982, updated on 22-Jun-2024

    Summary

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    Gene symbol
    mam4
    Gene description
    protein-S isoprenylcysteine O-methyltransferase Mam4
    Locus tag
    SPOM_SPAC10F6.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPAC10F6.12c
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    Genomic context

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    See mam4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1229095..1230272, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene mitotic/meiotic cohesin complex ATPase subunit Psm3/Smc3 Neighboring gene RIO family protein kinase Neighboring gene autophagy-associated protein kinase activator Atg17 Neighboring gene ncRNA Neighboring gene ABC1 kinase family protein Neighboring gene ncRNA Neighboring gene aspartate aminotransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinct functional relevance of dynamic GTPase cysteine methylation in fission yeast. Franco A, et al. Sci Rep, 2017 Jul 20. PMID 28729673, Free PMC Article
    2. Genes encoding farnesyl cysteine carboxyl methyltransferase in Schizosaccharomyces pombe and Xenopus laevis. Imai Y, et al. Mol Cell Biol, 1997 Mar. PMID 9032282, Free PMC Article
    3. The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast. Fontebasso Y, et al. DNA Repair (Amst), 2013 Dec. PMID 24192486, Free PMC Article
    4. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in C-terminal protein methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein-S isoprenylcysteine O-methyltransferase Mam4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1229095..1230272 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018660.3 → NP_593263.1  protein-S isoprenylcysteine O-methyltransferase Mam4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593263.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P87014
      Conserved Domains (1) summary
      COG2020
      Location:41 → 236
      STE14; Protein-S-isoprenylcysteine O-methyltransferase Ste14 [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version

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