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    rsc4 RSC complex bromodomain subunit Rsc4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539999, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rsc4
    Official Full Name
    RSC complex bromodomain subunit Rsc4
    Primary source
    PomBase:SPBC1734.15
    Locus tag
    SPOM_SPBC1734.15
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    brd1
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    Genomic context

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    See rsc4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (1088965..1091034)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cyclin-dependent protein kinase regulatory subunit Suc1 Neighboring gene SIN3 family co-repressor, Clr6 and Rpd3L histone deacetylase complex subunit Pst3 Neighboring gene ncRNA Neighboring gene chitin synthase-like protein 2 Neighboring gene ncRNA Neighboring gene valine--tRNA (Val) ligase Vrs1/Vas1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast. Wang Y, et al. J Biol Chem, 2012 Feb 3. PMID 22184112, Free PMC Article
    2. Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast. Monahan BJ, et al. Nat Struct Mol Biol, 2008 Aug. PMID 18622392, Free PMC Article
    3. A novel histone deacetylase complex in the control of transcription and genome stability. Zilio N, et al. Mol Cell Biol, 2014 Sep 15. PMID 25002536, Free PMC Article
    4. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Nguyen TT, et al. Sci Rep, 2015 Feb 11. PMID 25669599, Free PMC Article
    5. The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast. Fontebasso Y, et al. DNA Repair (Amst), 2013 Dec. PMID 24192486, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription elongation by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of RSC-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RSC-type complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    RSC complex bromodomain subunit Rsc4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1088965..1091034
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021340.3 → NP_595432.1  RSC complex bromodomain subunit Rsc4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595432.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09948
      Conserved Domains (2) summary
      smart00297
      Location:141 → 237
      BROMO; bromo domain
      COG5076
      Location:1 → 372
      COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
    Nucleotide Protein
    Heading Accession and Version

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