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    AAN1 Aan1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853787, updated on 2-Nov-2024

    Summary

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    Official Symbol
    AAN1
    Official Full Name
    Aan1p
    Primary source
    SGD:S000001558
    Locus tag
    YKL075C
    See related
    AllianceGenome:SGD:S000001558; FungiDB:YKL075C; VEuPathDB:YKL075C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in response to xenobiotic stimulus. Acts upstream of or within branched-chain amino acid metabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See AAN1 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (292956..294308, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene RNA helicase Neighboring gene Psg1p Neighboring gene Mud2p Neighboring gene Hsp70 family chaperone LHS1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast. Sing CN, et al. Nat Commun, 2022 May 16. PMID 35577788, Free PMC Article
    2. Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. Lee W, et al. PLoS Genet, 2005 Aug. PMID 16121259, Free PMC Article
    3. Spindle Position Checkpoint Kinase Kin4 Regulates Organelle Transport in Saccharomyces cerevisiae. Ekal L, et al. Biomolecules, 2023 Jul 10. PMID 37509134, Free PMC Article
    4. SWR1 chromatin remodeling complex prevents mitotic slippage during spindle position checkpoint arrest. Caydasi AK, et al. Mol Biol Cell, 2023 Feb 1. PMID 36542480, Free PMC Article
    5. The ribosome assembly factor Nop53 controls association of the RNA exosome with pre-60S particles in yeast. Cepeda LPP, et al. J Biol Chem, 2019 Dec 13. PMID 31662437, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast.
      Title: Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within branched-chain amino acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to xenobiotic stimulus HMP PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Aan1p
    NP_012848.1
    • hypothetical protein; regulates actin cable stability and branched-chain amino acid (BCAA) metabolism; involved in mitochondrial quality control and longevity; proposed to be involved in resistance to streptozotocin and camptothecin; localizes to punctate cytosolic structures

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      292956..294308 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179641.1 → NP_012848.1  TPA: Aan1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012848.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXL1, P36083
      UniProtKB/TrEMBL
      A6ZZP0, B3LR15, B5VM80, C7GVN2, C8ZC98, G2WHV6, N1P077
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36083.1

    Gene LinkOut

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