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    zrt1 plasma membrane ZIP zinc transmembrane transporter Zrt1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539655, updated on 18-Sep-2024

    Summary

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    Official Symbol
    zrt1
    Official Full Name
    plasma membrane ZIP zinc transmembrane transporter Zrt1
    Primary source
    PomBase:SPBC16D10.06
    Locus tag
    SPOM_SPBC16D10.06
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See zrt1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3607177..3609330)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene histone deacetylase, Sirtuin family, NAD-dependent Sir2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Response of Schizosaccharomyces pombe to zinc deficiency. Dainty SJ, et al. Eukaryot Cell, 2008 Mar. PMID 18203864, Free PMC Article
    2. Loss of Zhf and the tightly regulated zinc-uptake system SpZrt1 in Schizosaccharomyces pombe reveals the delicacy of cellular zinc balance. Boch A, et al. FEMS Yeast Res, 2008 Sep. PMID 18637840
    3. Zinc transporters belonging to the Cation Diffusion Facilitator (CDF) family have complementary roles in transporting zinc out of the cytosol. Choi S, et al. PLoS Genet, 2018 Mar. PMID 29529046, Free PMC Article
    4. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the tightly regulated Zrt1 (SPBC16D10.06)and Zhf contribute to cellular zinc homeostasis
      Title: Loss of Zhf and the tightly regulated zinc-uptake system SpZrt1 in Schizosaccharomyces pombe reveals the delicacy of cellular zinc balance.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables high-affinity zinc transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables high-affinity zinc transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables zinc ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in zinc ion import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in zinc ion import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in zinc ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plasma membrane ZIP zinc transmembrane transporter Zrt1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3607177..3609330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022422.3 → NP_596501.1  plasma membrane ZIP zinc transmembrane transporter Zrt1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596501.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94639
      Conserved Domains (1) summary
      pfam02535
      Location:60 → 405
      Zip; ZIP Zinc transporter
    Nucleotide Protein
    Heading Accession and Version

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