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    uro1 uricase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538957, updated on 18-Sep-2024

    Summary

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    Official Symbol
    uro1
    Official Full Name
    uricase
    Primary source
    PomBase:SPCC1223.09
    Locus tag
    SPOM_SPCC1223.09
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See uro1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1857150..1858233, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dihydrofolate reductase/ lysophospholipase fusion protein Dfr1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase II transcription elongation factor Eaf1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic studies of purine breakdown in the fission yeast Schizosaccharomyces pombe. Kinghorn JR, et al. Curr Genet, 1984 Feb. PMID 24177583
    2. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables urate oxidase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables urate oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in purine nucleobase catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in urate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in urea metabolic process IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uricase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1857150..1858233 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023345.3 → NP_588354.1  uricase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588354.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74409
      Conserved Domains (2) summary
      COG3648
      Location:1 → 296
      UriC; Uricase (urate oxidase) [Secondary metabolites biosynthesis, transport and catabolism]
      cl00263
      Location:12 → 295
      TFold; Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1), 6-pyrovoyl ...
    Nucleotide Protein
    Heading Accession and Version

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