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    vrg4 GDP-mannose transporter Vrg4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542850, updated on 22-Jun-2024

    Summary

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    Gene symbol
    vrg4
    Gene description
    GDP-mannose transporter Vrg4
    Locus tag
    SPOM_SPAC144.18
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPAC144.18
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    Genomic context

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    See vrg4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4690141..4691828)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase Neighboring gene sister chromatid cohesion protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cytoplasmic translation release factor class I eRF1 Neighboring gene ncRNA Neighboring gene multifunctional aromatic polypeptide Aro1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell wall integrity is compromised under temperature stress in Schizosaccharomyces pombe expressing a valproic acid-sensitive vas4 mutant. Qiao S, et al. Sci Rep, 2021 Jun 29. PMID 34188069, Free PMC Article
    2. Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast. Ma Y, et al. Genes Cells, 2009 Aug. PMID 19624755
    3. The conundrum of UDP-Glc entrance into the yeast ER lumen. Bredeston LM, et al. Glycobiology, 2017 Jan. PMID 27587357
    4. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cell wall integrity is compromised under temperature stress in Schizosaccharomyces pombe expressing a valproic acid-sensitive vas4 mutant.
      Title: Cell wall integrity is compromised under temperature stress in Schizosaccharomyces pombe expressing a valproic acid-sensitive vas4 mutant.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GDP-mannose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GDP-mannose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in GDP-mannose transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in GDP-mannose transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in Golgi membrane EXP
    Inferred from Experiment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GDP-mannose transporter Vrg4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4690141..4691828
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020108.3 → NP_594679.1  GDP-mannose transporter Vrg4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594679.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UTK8
      Conserved Domains (2) summary
      COG5070
      Location:7 → 321
      VRG4; Nucleotide-sugar transporter [Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
      cl23754
      Location:101 → 307
      EamA; EamA-like transporter family
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials