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    arc2 ARP2/3 actin-organizing complex subunit Arc34 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542287, updated on 10-Jul-2024

    Summary

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    Gene symbol
    arc2
    Gene description
    ARP2/3 actin-organizing complex subunit Arc34
    Locus tag
    SPOM_SPAC6F6.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    arc34
    Old locus tag
    SPAC6F6.10c
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    Genomic context

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    See arc2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2749724..2750982, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene NuA4 histone acetyltransferase complex subunit Eaf6 Neighboring gene ncRNA Neighboring gene pyridoxine-pyridoxal-pyridoxamine kinase Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit. Nolen BJ, et al. J Biol Chem, 2008 Sep 26. PMID 18640983, Free PMC Article
    2. Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. Skau CT, et al. J Biol Chem, 2011 Jul 29. PMID 21642440, Free PMC Article
    3. Pathway of actin filament branch formation by Arp2/3 complex. Beltzner CC, et al. J Biol Chem, 2008 Mar 14. PMID 18165685
    4. GMF is an evolutionarily developed Adf/cofilin-super family protein involved in the Arp2/3 complex-mediated organization of the actin cytoskeleton. Nakano K, et al. Cytoskeleton (Hoboken), 2010 Jun. PMID 20517925
    5. Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast. Sirotkin V, et al. J Cell Biol, 2005 Aug 15. PMID 16087707, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables actin filament binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables actin filament binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in Arp2/3 complex-mediated actin nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Arp2/3 complex-mediated actin nucleation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin cortical patch assembly IC
    Inferred by Curator
    more info
    		  
    involved_in actin filament branching EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in endocytosis IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Arp2/3 protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Arp2/3 protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in actin cortical patch IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in cell division site HDA PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    ARP2/3 actin-organizing complex subunit Arc34

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2749724..2750982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019333.3 → NP_593903.1  ARP2/3 actin-organizing complex subunit Arc34 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593903.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14241
      Conserved Domains (1) summary
      pfam04045
      Location:52 → 302
      P34-Arc; Arp2/3 complex, 34 kD subunit p34-Arc
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    3DWL_D.1
    3DWL_I.1

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