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    rpt2 19S proteasome base subcomplex ATPase subunit Rpt2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540939, updated on 22-Jun-2024

    Summary

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    Gene symbol
    rpt2
    Gene description
    19S proteasome base subcomplex ATPase subunit Rpt2
    Locus tag
    SPOM_SPBC4.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mts2
    Old locus tag
    SPBC4.07c
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    Genomic context

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    See rpt2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (1197778..1199428, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene acid phosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 5S ribosomal RNA Neighboring gene ncRNA Neighboring gene aspartate aminotransferase Maa1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mts4, a non-ATPase subunit of the 26 S protease in fission yeast is essential for mitosis and interacts directly with the ATPase subunit Mts2. Wilkinson CR, et al. J Biol Chem, 1997 Oct 10. PMID 9325304
    2. Sum1, a component of the fission yeast eIF3 translation initiation complex, is rapidly relocalized during environmental stress and interacts with components of the 26S proteasome. Dunand-Sauthier I, et al. Mol Biol Cell, 2002 May. PMID 12006658, Free PMC Article
    3. Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the Pap1 transcription factor. Penney M, et al. PLoS One, 2012. PMID 23209828, Free PMC Article
    4. Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast. Stone M, et al. J Mol Biol, 2004 Nov 26. PMID 15533439
    5. Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteins. Seeger M, et al. J Biol Chem, 2003 May 9. PMID 12615927

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity NAS
    Non-traceable Author Statement
    more info
    		  
    enables proteasome-activating activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables proteasome-activating activity ISM
    Inferred from Sequence Model
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasomal protein catabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of proteasome regulatory particle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome regulatory particle, base subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proteasome regulatory particle, base subcomplex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    19S proteasome base subcomplex ATPase subunit Rpt2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1197778..1199428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021391.3 → NP_595480.1  19S proteasome base subcomplex ATPase subunit Rpt2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595480.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P36612
      Conserved Domains (3) summary
      PTZ00361
      Location:1 → 448
      PTZ00361; 26 proteosome regulatory subunit 4-like protein; Provisional
      pfam00004
      Location:228 → 361
      AAA; ATPase family associated with various cellular activities (AAA)
      pfam16450
      Location:115 → 167
      Prot_ATP_ID_OB; Proteasomal ATPase OB/ID domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    2001429A.1

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