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    CTR86 Ctr86p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850421, updated on 17-May-2024

    Summary

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    Gene symbol
    CTR86
    Gene description
    Ctr86p
    Primary source
    FungiDB:YCR054C
    Locus tag
    YCR054C
    See related
    SGD:S000000650; AllianceGenome:SGD:S000000650; VEuPathDB:YCR054C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in threonine biosynthetic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 10. Orthologous to human ATXN10 (ataxin 10). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CTR86 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (218376..220067, complement)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene Rsc6p Neighboring gene threonine synthase THR4 Neighboring gene snoRNA-binding rRNA-processing protein PWP2 Neighboring gene Yih1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale phenotypic analysis--the pilot project on yeast chromosome III. Rieger KJ, et al. Yeast, 1997 Dec. PMID 9509574
    2. Analysis of the THR4 region on chromosome III of the yeast Saccharomyces cerevisiae. Mannhaupt G, et al. Yeast, 1990 Jul-Aug. PMID 2204248
    3. 14-3-3 Protein Bmh1 triggers short-range compaction of mitotic chromosomes by recruiting sirtuin deacetylase Hst2. Jain N, et al. J Biol Chem, 2021 Jan-Jun. PMID 33187982, Free PMC Article
    4. The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis. Lacoux C, et al. Nucleic Acids Res, 2020 Dec 2. PMID 33166396, Free PMC Article
    5. The complete DNA sequence of yeast chromosome III. Oliver SG, et al. Nature, 1992 May 7. PMID 1574125

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Ctr86p
    NP_009983.1
    • Essential hypothetical protein; with orthologs in Ashbya gossypii and Candida albicans; similar to human ATXN10, mutations in which cause spinocerebellar ataxia type 10; codon usage corresponds to that observed for yeast genes expressed at low levels; relative distribution to the nucleus increases upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      218376..220067 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178768.1 → NP_009983.1  TPA: Ctr86p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009983.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VR62, P25355
      UniProtKB/TrEMBL
      A0A8H4BUP7, A6ZTN3, B3LUB7, B5VEZ2, C7GJT2, C8Z4E6, G2WA69
      Conserved Domains (1) summary
      pfam09759
      Location:446 → 544
      Atx10homo_assoc; Spinocerebellar ataxia type 10 protein domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25355.1

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