dis3 3'-5' exoribonuclease subunit Dis3 [Schizosaccharomyces pombe (fission yeast)] - Gene

Summary

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Official Symbol: dis3
Official Full Name: 3'-5' exoribonuclease subunit Dis3
Primary source: PomBase:SPBC26H8.10
Locus tag: SPOM_SPBC26H8.10
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Schizosaccharomyces pombe (strain: 972h-)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as: rrp44
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Genomic context

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See dis3 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 2

Sequence:: Chromosome: II; NC_003423.3 (3970969..3974218)

Chromosome II - NC_003423.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by PomBase

Function	Evidence Code	Pubs
enables 3'-5'-RNA exonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3'-5'-RNA exonuclease activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA endonuclease activity	ISO Inferred from Sequence Orthology more info
enables RNA exonuclease activity	IDA Inferred from Direct Assay more info	PubMed
enables RNA nuclease activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables endonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables small GTPase binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in RNA catabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in TRAMP-dependent tRNA surveillance pathway	ISO Inferred from Sequence Orthology more info
involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	ISO Inferred from Sequence Orthology more info
involved_in exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	ISO Inferred from Sequence Orthology more info
involved_in nonfunctional rRNA decay	ISO Inferred from Sequence Orthology more info
involved_in nuclear RNA surveillance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nuclear mRNA surveillance of mRNA 3'-end processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in nuclear mRNA surveillance of mRNA 3'-end processing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nuclear polyadenylation-dependent mRNA catabolic process	ISO Inferred from Sequence Orthology more info
involved_in nuclear polyadenylation-dependent rRNA catabolic process	ISO Inferred from Sequence Orthology more info
involved_in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay	ISO Inferred from Sequence Orthology more info
involved_in nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nuclear-transcribed mRNA catabolic process, non-stop decay	ISO Inferred from Sequence Orthology more info
involved_in rRNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in termination of RNA polymerase II transcription, exosome-dependent	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in chromatin	IDA Inferred from Direct Assay more info	PubMed
part_of cytoplasmic exosome (RNase complex)	IBA Inferred from Biological aspect of Ancestor more info
part_of exosome (RNase complex)	IDA Inferred from Direct Assay more info	PubMed
part_of nuclear exosome (RNase complex)	EXP Inferred from Experiment more info	PubMed
part_of nuclear exosome (RNase complex)	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nuclear exosome focus	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	HDA more info	PubMed
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: 3'-5' exoribonuclease subunit Dis3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003423.3 Reference assembly

Range

3970969..3974218

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001022575.3 → NP_596653.1 3'-5' exoribonuclease subunit Dis3 [Schizosaccharomyces pombe]

See identical proteins and their annotated locations for NP_596653.1

Status: PROVISIONAL

UniProtKB/Swiss-Prot

P37202

Conserved Domains (3) summary

cd09862
Location:23 → 213

PIN_Rrp44; PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs

COG0557
Location:289 → 958

VacB; Exoribonuclease R [Transcription]

pfam00773
Location:496 → 827

RNB; RNB domain