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    tfx1 translin family protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539455, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tfx1
    Official Full Name
    translin family protein
    Primary source
    PomBase:SPCC736.09c
    Locus tag
    SPOM_SPCC736.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See tfx1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (329570..330603, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor, CBF1/Su(H)/LAG-1 family Cbf11 Neighboring gene ncRNA Neighboring gene tRNA-Phe Neighboring gene ncRNA Neighboring gene mitochondrial 37S ribosomal protein uS8m

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mapping of interaction sites of the Schizosaccharomyces pombe protein Translin with nucleic acids and proteins: a combined molecular genetics and bioinformatics study. Eliahoo E, et al. Nucleic Acids Res, 2010 May. PMID 20081200, Free PMC Article
    2. Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX. Jaendling A, et al. Biochim Biophys Acta, 2008 Feb. PMID 18062930
    3. Cloning and characterization of the Schizosaccharomyces pombe homologs of the human protein Translin and the Translin-associated protein TRAX. Laufman O, et al. Nucleic Acids Res, 2005. PMID 16043634, Free PMC Article
    4. Biochemical characterization of clinically relevant mutations of human Translin. Pillai V, et al. Mol Cell Biochem, 2023 Apr. PMID 36098897
    5. Identification of proteins that form specific complexes with the highly conserved protein Translin in Schizosaccharomyces pombe. Eliahoo E, et al. Biochim Biophys Acta, 2014 Apr. PMID 24382491

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. TRAX is a non-essential protein that interacts with the translin protein. [trax]
      Title: Cloning and characterization of the Schizosaccharomyces pombe homologs of the human protein Translin and the Translin-associated protein TRAX.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing TAS
    Traceable Author Statement
    more info
    		 PubMed 
    NOT involved_in double-strand break repair via homologous recombination TAS
    Traceable Author Statement
    more info
    		 PubMed 
    NOT involved_in double-strand break repair via nonhomologous end joining TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    translin family protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      329570..330603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022773.3 → NP_587780.1  translin family protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587780.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74955
      Conserved Domains (1) summary
      COG2178
      Location:1 → 219
      COG2178; Predicted RNA- or ssDNA-binding protein, translin family [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version

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