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    cfr1 CHS5-like protein Cfr1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541978, updated on 22-Jun-2024

    Summary

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    Gene symbol
    cfr1
    Gene description
    CHS5-like protein Cfr1
    Locus tag
    SPOM_SPAC6G9.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPAC6G9.12
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    Genomic context

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    See cfr1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3270197..3272367)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene helicase Sen1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene synaptobrevin family receptor Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene bouquet formation protein Bqt1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The FN3 and BRCT motifs in the exomer component Chs5p define a conserved module that is necessary and sufficient for its function. Martín-García R, et al. Cell Mol Life Sci, 2011 Sep. PMID 21113731, Free PMC Article
    2. The Schizosaccharomyces pombe cfr1+ gene participates in mating through a new pathway that is independent of fus1+. Cartagena-Lirola H, et al. Yeast, 2006 Apr 15. PMID 16598689
    3. Traffic Through the Trans-Golgi Network and the Endosomal System Requires Collaboration Between Exomer and Clathrin Adaptors in Fission Yeast. Hoya M, et al. Genetics, 2017 Feb. PMID 27974503, Free PMC Article
    4. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
    5. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cfr1 and Bch1 proteins constitute the simplest form of an exomer. Cfr1 co-immunoprecipitates with AP-1, AP-2, and GGA subunits.
      Title: Traffic Through the Trans-Golgi Network and the Endosomal System Requires Collaboration Between Exomer and Clathrin Adaptors in Fission Yeast.
    2. In Schizosaccharomyces pombe, the cfr1+ gene participates in mating through a new pathway that is independent of fus1+.
      Title: The Schizosaccharomyces pombe cfr1+ gene participates in mating through a new pathway that is independent of fus1+.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to endosome transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in Golgi to plasma membrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi to vacuole transport IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    NOT involved_in chitin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in conjugation with cellular fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    NOT involved_in glucan biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in early endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of exomer complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of exomer complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CHS5-like protein Cfr1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3270197..3272367
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019545.3 → NP_594121.1  CHS5-like protein Cfr1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594121.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q92357
      Conserved Domains (3) summary
      smart00292
      Location:169 → 242
      BRCT; breast cancer carboxy-terminal domain
      cd13945
      Location:5 → 77
      Chs5_N; N-terminal dimerization domain of Chs5 and similar proteins
      pfam16893
      Location:78 → 166
      fn3_2; Fibronectin type III domain
    Nucleotide Protein
    Heading Accession and Version

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