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    RPL27B ribosomal 60S subunit protein L27B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852082, updated on 9-Jun-2024

    Summary

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    Gene symbol
    RPL27B
    Gene description
    ribosomal 60S subunit protein L27B
    Primary source
    FungiDB:YDR471W
    Locus tag
    YDR471W
    See related
    SGD:S000002879; AllianceGenome:SGD:S000002879; VEuPathDB:YDR471W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of preribosome, large subunit precursor. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPL27B in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_001136.10 (1401770..1402564)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Sdc1p Neighboring gene Ugo1p Neighboring gene ncRNA Neighboring gene TRAPP subunit TRS31

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lithium Chloride Sensitivity in Yeast and Regulation of Translation. Hajikarimlou M, et al. Int J Mol Sci, 2020 Aug 10. PMID 32785068, Free PMC Article
    2. Quantitative proteomic analysis of ribosomal protein L35b mutant of Saccharomyces cerevisiae. Song YB, et al. Biochim Biophys Acta, 2010 Apr. PMID 19879384
    3. Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae. Pöll G, et al. PLoS One, 2017. PMID 28686620, Free PMC Article
    4. Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways. Ikeuchi K, et al. EMBO J, 2019 Mar 1. PMID 30609991, Free PMC Article
    5. Unifying fluorescence microscopy and mass spectrometry for studying protein complexes in cells. Deng C, et al. Mol Cell Proteomics, 2009 Jun. PMID 19269952, Free PMC Article

    See all (70) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of preribosome, large subunit precursor IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L27B
    NP_010759.1
    • Ribosomal 60S subunit protein L27B; homologous to mammalian ribosomal protein L27, no bacterial homolog; RPL27B has a paralog, RPL27A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1401770..1402564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180779.1 → NP_010759.1  TPA: ribosomal 60S subunit protein L27B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010759.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT95, P0C2H7
      UniProtKB/TrEMBL
      C7GMQ1
      Conserved Domains (2) summary
      COG2163
      Location:1 → 128
      RPL14A; Ribosomal protein L14E/L6E/L27E [Translation, ribosomal structure and biogenesis]
      cl00354
      Location:1 → 136
      KOW; KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C2H7.1

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