U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RIM1 Rim1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850395, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RIM1
    Official Full Name
    Rim1p
    Primary source
    SGD:S000007222
    Locus tag
    YCR028C-A
    See related
    AllianceGenome:SGD:S000007222; FungiDB:YCR028C-A; VEuPathDB:YCR028C-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables single-stranded DNA binding activity. Involved in mitochondrial genome maintenance and positive regulation of mitochondrial DNA replication. Located in mitochondrial nucleoid. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human SSBP1 (single stranded DNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RIM1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_001135.5 (172950..173440, complement)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene tRNA-Gln Neighboring gene Fen2p Neighboring gene Syp1p Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Glucose repression on RIM1, a gene encoding a mitochondrial single-stranded DNA-binding protein, in Saccharomyces cerevisiae: a possible regulation at pre-mRNA splicing. Li Z, et al. Curr Genet, 1998 Dec. PMID 9871116
    2. The mitochondrial single-stranded DNA binding protein from S. cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers. Singh SP, et al. Nucleic Acids Res, 2018 Aug 21. PMID 29931186, Free PMC Article
    3. Analysis of Protein-protein Interaction Interface between Yeast Mitochondrial Proteins Rim1 and Pif1 Using Chemical Cross-linking Mass Spectrometry. Zybailov B, et al. J Proteomics Bioinform, 2015 Nov. PMID 26807012, Free PMC Article
    4. Physical and functional interaction between yeast Pif1 helicase and Rim1 single-stranded DNA binding protein. Ramanagoudr-Bhojappa R, et al. Nucleic Acids Res, 2013 Jan. PMID 23175612, Free PMC Article
    5. Mitochondrial telomere-binding protein from Candida parapsilosis suggests an evolutionary adaptation of a nonspecific single-stranded DNA-binding protein. Nosek J, et al. J Biol Chem, 1999 Mar 26. PMID 10085128

    See all (90) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results show a direct physical interaction between Pif1 helicase and Rim1 regulated by two binding regions on each of the proteins.
      Title: Physical and functional interaction between yeast Pif1 helicase and Rim1 single-stranded DNA binding protein.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial DNA replication ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in mitochondrial genome maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of mitochondrial DNA replication IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrial nucleoid IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial nucleoid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Rim1p
    NP_009958.2
    • ssDNA-binding protein essential for mitochondrial genome maintenance; involved in mitochondrial DNA replication; stimulates utilization by Mip1p DNA polymerase of RNA primers synthesized by Rpo41p

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      172950..173440 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184315.1 → NP_009958.2  TPA: Rim1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009958.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VR39, O11851, P32445
      UniProtKB/TrEMBL
      A6ZTL0, B3LUA0, C7GQ17, G2WA47, N1P844
      Conserved Domains (1) summary
      pfam00436
      Location:19 → 116
      SSB; Single-strand binding protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32445.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous