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    gnd1 phosphogluconate dehydrogenase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541146, updated on 22-Jun-2024

    Summary

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    Gene symbol
    gnd1
    Gene description
    phosphogluconate dehydrogenase
    Locus tag
    SPOM_SPBC660.16
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPBC660.16
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    Genomic context

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    See gnd1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003423.3 (230322..233218)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene cleavage factor complex subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene autophagy-associated protein Atg2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and kinetic characterization of 6-phosphogluconate dehydrogenase from Schizosaccharomyces pombe. Tsai CS, et al. Biochem Cell Biol, 1998. PMID 10099784
    2. Kinetic studies of gluconate pathway enzymes from Schizosaccharomyces pombe. Tsai CS, et al. Arch Biochem Biophys, 1995 Jan 10. PMID 7840612
    3. Carbon-13 NMR studies and purification of gluconate pathway enzymes from Schizosaccharomyces pombe. Tsai CS, et al. Arch Biochem Biophys, 1995 Jan 10. PMID 7840611
    4. Repression of enzymes of the pentose phosphate pathway by glucose in fission yeast. Mehta S, et al. FEBS Lett, 1998 Dec 4. PMID 9872416
    5. Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1. Kilchert C, et al. Cell Rep, 2015 Dec 22. PMID 26670050, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables NADP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables NADP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphogluconate dehydrogenase (decarboxylating) activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables phosphogluconate dehydrogenase (decarboxylating) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphogluconate dehydrogenase (decarboxylating) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-gluconate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in D-gluconate catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glycolytic process via Entner-Doudoroff Pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pentose-phosphate shunt, oxidative branch EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in pentose-phosphate shunt, oxidative branch IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pentose-phosphate shunt, oxidative branch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    phosphogluconate dehydrogenase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      230322..233218
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021002.3 → NP_595095.1  phosphogluconate dehydrogenase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595095.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78812, Q9UQW5
      Conserved Domains (3) summary
      COG0362
      Location:5 → 484
      Gnd; 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]
      pfam00393
      Location:183 → 478
      6PGD; 6-phosphogluconate dehydrogenase, C-terminal domain
      pfam03446
      Location:7 → 179
      NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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