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    eng2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541480, updated on 22-Aug-2024

    Summary

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    Official Symbol
    eng2
    Primary source
    PomBase:SPAC23D3.10c
    Locus tag
    SPOM_SPAC23D3.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See eng2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4355410..4358192, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene proteasome core particle subunit beta 2 Neighboring gene U1 snRNP-associated protein Usp108 Neighboring gene SWI/SNF and RSC complex subunit Arp42 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 1-acyldihydroxyacetone phosphate reductase Neighboring gene ncRNA Neighboring gene inorganic phosphate transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Eng2, a new player involved in feedback loop regulation of Cdc42 activity in fission yeast. García P, et al. Sci Rep, 2021 Sep 9. PMID 34504165, Free PMC Article
    2. Eng2 is a component of a dynamic protein complex required for endocytic uptake in fission yeast. Encinar del Dedo J, et al. Traffic, 2014 Oct. PMID 25040903
    3. A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast. Dudin O, et al. J Cell Biol, 2015 Mar 30. PMID 25825517, Free PMC Article
    4. {beta}-glucanase Eng2 is required for ascus wall endolysis after sporulation in the fission yeast Schizosaccharomyces pombe. Encinar del Dedo J, et al. Eukaryot Cell, 2009 Aug. PMID 19542306, Free PMC Article
    5. Global coordination of transcriptional control and mRNA decay during cellular differentiation. Amorim MJ, et al. Mol Syst Biol, 2010 Jun 8. PMID 20531409, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Eng2 probably couples the endocytic coat to the actin module.
      Title: Eng2 is a component of a dynamic protein complex required for endocytic uptake in fission yeast.
    2. Eng2 acts together with Agn2 to completely hydrolyze the ascus wall, thereby assisting in the release of ascospores in S. pombe.
      Title: {beta}-glucanase Eng2 is required for ascus wall endolysis after sporulation in the fission yeast Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables glucan endo-1,3-beta-D-glucosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucan endo-1,3-beta-D-glucosidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in bipolar cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell wall polysaccharide catabolic process IC
    Inferred by Curator
    more info
    		  
    involved_in endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in extracellular polysaccharide catabolic process involved in ascospore release from ascus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in fungal-type cell wall disassembly involved in conjugation with cellular fusion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in maintenance of protein location in cell cortex of cell tip IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in ascus epiplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in fungal-type cell wall IC
    Inferred by Curator
    more info
    		  
    is_active_in mating projection actin fusion focus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cell wall and ascospore endo-1,3-beta-glucanase Eng2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4355410..4358192 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019976.3 → NP_594547.1  cell wall and ascospore endo-1,3-beta-glucanase Eng2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594547.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09850
      Conserved Domains (1) summary
      COG5498
      Location:1 → 706
      Acf2; Endoglucanase Acf2 [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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