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    mud1 UBA domain protein Mud1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361477, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mud1
    Official Full Name
    UBA domain protein Mud1
    Primary source
    PomBase:SPAC56F8.08
    Locus tag
    SPOM_SPAC56F8.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ddi1; ucp1
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    Genomic context

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    See mud1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (1139094..1140325)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene dolichyl-phosphate-glucose--glycolipid alpha-glucosyltransferase Alg10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein ema19 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene rRNA methyltransferase Rrp8 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain. Trempe JF, et al. EMBO J, 2005 Sep 21. PMID 16138082, Free PMC Article
    2. Click synthesis of ubiquitin dimer analogs to interrogate linkage-specific UBA domain binding. Weikart ND, et al. Chem Commun (Camb), 2012 Jan 7. PMID 22095407
    3. UBA domain containing proteins in fission yeast. Hartmann-Petersen R, et al. Int J Biochem Cell Biol, 2003 May. PMID 12672455
    4. BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation. Wiggins CM, et al. J Cell Sci, 2011 Mar 15. PMID 21378313
    5. Proteins containing the UBA domain are able to bind to multi-ubiquitin chains. Wilkinson CR, et al. Nat Cell Biol, 2001 Oct. PMID 11584278

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables K48-linked polyubiquitin modification-dependent protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables SNARE binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polyubiquitin modification-dependent protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of exocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    UBA domain protein Mud1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1139094..1140325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018619.3 → NP_001018195.1  UBA domain protein Mud1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_001018195.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10256
      Conserved Domains (2) summary
      pfam09668
      Location:87 → 210
      Asp_protease; Aspartyl protease
      cd14308
      Location:297 → 332
      UBA_Mud1_like; UBA domain found in Schizosaccharomyces pombe UBA domain-containing protein mud1 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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