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    aldose 1-epimerase superfamily protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855808, updated on 18-Sep-2024

    Summary

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    Official Full Name
    aldose 1-epimerase superfamily protein
    Primary source
    SGD:S000005354
    Locus tag
    YNR071C
    See related
    AllianceGenome:SGD:S000005354; FungiDB:YNR071C; VEuPathDB:YNR071C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose and glucose metabolic process. Human ortholog(s) of this gene implicated in galactosemia. Orthologous to human GALM (galactose mutarotase). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (770440..771468, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Bsc5p Neighboring gene ATP-binding cassette multidrug transporter PDR18 Neighboring gene hexose transporter HXT17 Neighboring gene putative mannitol dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Investigation of the functional role of aldose 1-epimerase in engineered cellobiose utilization. Li S, et al. J Biotechnol, 2013 Oct 10. PMID 23954547
    2. Characterization of the interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae. Piya G, et al. PLoS One, 2015. PMID 25719602, Free PMC Article
    3. Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Fillingham J, et al. Mol Cell Biol, 2008 Jul. PMID 18458063, Free PMC Article
    4. Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications. Nitika, et al. PLoS Biol, 2022 Oct. PMID 36269765, Free PMC Article
    5. The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. Atencio D, et al. G3 (Bethesda), 2014 Mar 20. PMID 24470217, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables aldose 1-epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in galactose catabolic process via UDP-galactose IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glucose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    aldose 1-epimerase superfamily protein
    NP_014469.1
    • Putative aldose 1-epimerase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      770440..771468 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183248.1 → NP_014469.1  TPA: aldose 1-epimerase superfamily protein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014469.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1P6, P53757
      UniProtKB/TrEMBL
      A6ZSE5, B3LPH3, B5VR96, C7GM68, C8ZFU8
      Conserved Domains (1) summary
      cd09019
      Location:13 → 340
      galactose_mutarotase_like; galactose mutarotase_like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53757.1

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