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    fnp1 folliculin complex subunit fnp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543076, updated on 18-Sep-2024

    Summary

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    Official Symbol
    fnp1
    Official Full Name
    folliculin complex subunit fnp1
    Primary source
    PomBase:SPAC30C2.07
    Locus tag
    SPOM_SPAC30C2.07
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    lst4
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    Genomic context

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    See fnp1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4642307..4645177)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cornichon family protein Erv14 Neighboring gene ncRNA Neighboring gene GTPase dml1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene voltage-dependent anion channel protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
    2. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of TORC1 signaling EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in positive regulation of TORC1 signaling EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of FNIP-folliculin RagC/D GAP EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in vacuolar membrane EXP
    Inferred from Experiment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    folliculin complex subunit fnp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4642307..4645177
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020088.3 → NP_594659.1  folliculin complex subunit fnp1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594659.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P6K4
      Conserved Domains (1) summary
      pfam14636
      Location:72 → 101
      FNIP_N; Folliculin-interacting protein N-terminus
    Nucleotide Protein
    Heading Accession and Version

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