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    WWM1 Wwm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850538, updated on 9-Jun-2024

    Summary

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    Gene symbol
    WWM1
    Gene description
    Wwm1p
    Primary source
    FungiDB:YFL010C
    Locus tag
    YFL010C
    See related
    SGD:S000001884; AllianceGenome:SGD:S000001884; VEuPathDB:YFL010C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in apoptotic process. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See WWM1 in Genome Data Viewer
    Location:
    chromosome: VI
    Exon count:
    1
    Sequence:
    Chromosome: VI; NC_001138.5 (115108..115743, complement)

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene hexose transporter HXT10 Neighboring gene Aua1p Neighboring gene SCF ubiquitin ligase complex subunit CDC4 Neighboring gene cohesin subunit SMC1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001138.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. Szallies A, et al. FEBS Lett, 2002 Apr 24. PMID 12062425
    2. A caspase-related protease regulates apoptosis in yeast. Madeo F, et al. Mol Cell, 2002 Apr. PMID 11983181
    3. Highly hydrophilic proteins in prokaryotes and eukaryotes are common during conditions of water deficit. Garay-Arroyo A, et al. J Biol Chem, 2000 Feb 25. PMID 10681550
    4. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Stevenson LF, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11274415, Free PMC Article
    5. The influence of HMF and furfural on redox-balance and energy-state of xylose-utilizing Saccharomyces cerevisiae. Ask M, et al. Biotechnol Biofuels, 2013 Feb 15. PMID 23409974, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Wwm1p
    NP_570898.1
    • WW domain containing hypothetical protein; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes G1 phase growth arrest and clonal death that is suppressed by overexpression of MCA1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5 Reference assembly

      Range
      115108..115743 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179956.1 → NP_570898.1  TPA: Wwm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_570898.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTM0, P43582
      UniProtKB/TrEMBL
      A0A8H8UL74, A7A229, B3LUK0, C7GY99, C8Z7S7
      Conserved Domains (1) summary
      pfam00397
      Location:12 → 41
      WW; WW domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43582.1

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