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    spt20 SAGA complex subunit Spt20 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543675, updated on 17-May-2024

    Summary

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    Gene symbol
    spt20
    Gene description
    SAGA complex subunit Spt20
    Primary source
    PomBase:SPAC4D7.10c
    Locus tag
    SPAC4D7.10c
    See related
    FungiDB:SPAC4D7.10c; VEuPathDB:SPAC4D7.10c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See spt20 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003424.3 (5369400..5371874, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene putative translation initiation factor eIF2B gamma subunit tif223 Neighboring gene miscRNA Neighboring gene protein dsc4 Neighboring gene protein new13 Neighboring gene putative ATP binding protein Fet5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [SAGA complex subunit Spt20 involves in the calcineurin-mediated Cl- homeostasis in Schizosaccharomyces pombe]. Zhou N, et al. Yi Chuan, 2013 Sep. PMID 24400488
    2. Septin ring assembly is regulated by Spt20, a structural subunit of the SAGA complex. Lei B, et al. J Cell Sci, 2014 Sep 15. PMID 25015293
    3. Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin. Bao K, et al. Genes Dev, 2019 Jan 1. PMID 30573453, Free PMC Article
    4. The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. Helmlinger D, et al. Genes Dev, 2008 Nov 15. PMID 19056896, Free PMC Article
    5. Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex. Helmlinger D, et al. EMBO J, 2011 Jun 3. PMID 21642955, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SAGA complex subunit Spt20 involves in the calcineurin-mediated Cl- homeostasis.
      Title: [SAGA complex subunit Spt20 involves in the calcineurin-mediated Cl- homeostasis in Schizosaccharomyces pombe].
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in septin ring organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in septin ring organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SAGA complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in medial cortex septin ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SAGA complex subunit Spt20

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5369400..5371874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356204.1 → NP_001342846.1  SAGA complex subunit Spt20 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14174
      Conserved Domains (1) summary
      pfam12090
      Location:53 → 240
      Spt20; Spt20 family
    Nucleotide Protein
    Heading Accession and Version

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