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    cki3 serine/threonine protein kinase (CK1 family) Cki3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542395, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cki3
    Official Full Name
    serine/threonine protein kinase (CK1 family) Cki3
    Primary source
    PomBase:SPAC1805.05
    Locus tag
    SPOM_SPAC1805.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See cki3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (2781152..2783133)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene nucleoporin, WD repeat Nup132 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene porphobilinogen synthase Hem2 Neighboring gene DASH complex subunit Dad2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Casein kinase 1γ acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast. Koyano T, et al. Genes Cells, 2015 Dec. PMID 26525038, Free PMC Article
    2. Casein kinase 1γ ensures monopolar growth polarity under incomplete DNA replication downstream of Cds1 and calcineurin in fission yeast. Koyano T, et al. Mol Cell Biol, 2015 May. PMID 25691662, Free PMC Article
    3. Search for kinases related to transition of growth polarity in fission yeast. Koyano T, et al. Biosci Biotechnol Biochem, 2010. PMID 20501954
    4. Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. Tanae K, et al. PLoS One, 2012. PMID 22291963, Free PMC Article
    5. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Study proposes that Cki3 monitors the timing of growth polarity transition from monopolar to bipolar during G2 phase onset through Tea1 phosphorylation by regulating the interaction between Tea1 and Tea4.
      Title: Casein kinase 1γ acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast.
    2. The fission yeast Cki3 (a casein kinase 1gamma homolog) is a critical regulator to ensure persistent monopolar growth during S phase.
      Title: Casein kinase 1γ ensures monopolar growth polarity under incomplete DNA replication downstream of Cds1 and calcineurin in fission yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables protein kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of establishment of bipolar cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of protein localization to cell tip IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of endocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine protein kinase (CK1 family) Cki3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2781152..2783133
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019345.3 → NP_593916.1  serine/threonine protein kinase (CK1 family) Cki3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593916.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74135
      Conserved Domains (2) summary
      COG0515
      Location:14 → 353
      SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
      cl21453
      Location:14 → 290
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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