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    thi2 thiazole biosynthetic enzyme [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540526, updated on 22-Jun-2024

    Summary

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    Gene symbol
    thi2
    Gene description
    thiazole biosynthetic enzyme
    Locus tag
    SPOM_SPBC26H8.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    nmt2
    Old locus tag
    SPBC26H8.01
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    Genomic context

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    See thi2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3940526..3941699)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene tRNA-Asp Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein transport protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. nmt2 of fission yeast: a second thiamine-repressible gene co-ordinately regulated with nmt1. Manetti AG, et al. Yeast, 1994 Aug. PMID 7992507
    2. Thiamine in Schizosaccharomyces pombe: dephosphorylation, intracellular pool, biosynthesis and transport. Schweingruber AM, et al. Curr Genet, 1991 Apr. PMID 1868574
    3. Characterization of Thi9, a novel thiamine (Vitamin B1) transporter from Schizosaccharomyces pombe. Vogl C, et al. J Biol Chem, 2008 Mar 21. PMID 18201975
    4. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article
    5. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pentosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in thiamine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in thiazole biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    thiazole biosynthetic enzyme

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3940526..3941699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022564.3 → NP_596642.1  thiazole biosynthetic enzyme [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596642.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74785, P40998
      Conserved Domains (2) summary
      TIGR00292
      Location:56 → 311
      TIGR00292; thiazole biosynthesis enzyme
      pfam01946
      Location:60 → 299
      Thi4; Thi4 family
    Nucleotide Protein
    Heading Accession and Version

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