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    VMA9 H(+)-transporting V0 sector ATPase subunit e [ Saccharomyces cerevisiae S288C ]

    Gene ID: 2732686, updated on 29-Jun-2024

    Summary

    Gene symbol
    VMA9
    Gene description
    H(+)-transporting V0 sector ATPase subunit e
    Primary source
    FungiDB:YCL005W-A
    Locus tag
    YCL005W-A
    See related
    SGD:S000028508; AllianceGenome:SGD:S000028508; VEuPathDB:YCL005W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CWH36; LDB10
    Summary
    Enables ATPase-coupled ion transmembrane transporter activity. Involved in several processes, including cell wall mannoprotein biosynthetic process; cellular protein-containing complex assembly; and vacuolar acidification. Located in fungal-type vacuole membrane. Part of vacuolar proton-transporting V-type ATPase, V0 domain. Orthologous to human ATP6V0E1 (ATPase H+ transporting V0 subunit e1) and ATP6V0E2 (ATPase H+ transporting V0 subunit e2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See VMA9 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_001135.5 (107023..107417)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene acetolactate synthase regulatory subunit Neighboring gene ubiquitin-binding ESCRT-I subunit protein STP22 Neighboring gene ncRNA Neighboring gene Ldb16p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in cell wall mannoprotein biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein-containing complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein-containing complex assembly IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vacuolar acidification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vacuolar acidification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in fungal-type vacuole membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of proton-transporting V-type ATPase, V0 domain IEA
    Inferred from Electronic Annotation
    more info
     
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of vacuolar proton-transporting V-type ATPase, V0 domain IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of vacuolar proton-transporting V-type ATPase, V0 domain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    H(+)-transporting V0 sector ATPase subunit e
    NP_958835.1
    • Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      107023..107417
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184518.1NP_958835.1  TPA: H(+)-transporting V0 sector ATPase subunit e [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_958835.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VR05, Q3E7B6
      UniProtKB/TrEMBL
      A6ZTH7, B3LU68, C8Z479, G2WA13
      Conserved Domains (1) summary
      pfam05493
      Location:663
      ATP_synt_H; ATP synthase subunit H