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    BSC6 Bsc6p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853983, updated on 29-Jun-2024

    Summary

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    Gene symbol
    BSC6
    Gene description
    Bsc6p
    Primary source
    FungiDB:YOL137W
    Locus tag
    YOL137W
    See related
    SGD:S000005497; AllianceGenome:SGD:S000005497; VEuPathDB:YOL137W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Colocalizes with COPI-coated vesicle and clathrin-coated vesicle. Orthologous to human MFSD4B (major facilitator superfamily domain containing 4B). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See BSC6 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (65621..67114)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene translation initiation factor eIF4E Neighboring gene Rtc1p Neighboring gene 6-phosphofructo-2-kinase Neighboring gene mediator complex subunit MED7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of stop codon readthrough genes in Saccharomyces cerevisiae. Namy O, et al. Nucleic Acids Res, 2003 May 1. PMID 12711673, Free PMC Article
    2. A split-ubiquitin two-hybrid screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2. Van Zeebroeck G, et al. PLoS One, 2011. PMID 21912684, Free PMC Article
    3. A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p). Millson SH, et al. Eukaryot Cell, 2005 May. PMID 15879519, Free PMC Article
    4. Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes. Lamb NA, et al. Genetics, 2022 Jul 30. PMID 35686905, Free PMC Article
    5. Reconstitution and protein composition analysis of endocytic actin patches. Michelot A, et al. Curr Biol, 2010 Nov 9. PMID 21035341, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in COPI-coated vesicle HDA PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in clathrin-coated vesicle HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Bsc6p
    NP_014504.1
    • hypothetical protein with 8 putative transmembrane segments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      65621..67114
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183391.1 → NP_014504.1  TPA: Bsc6p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014504.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1T2, Q08280, Q6B229
      UniProtKB/TrEMBL
      A0A6A5Q3T1, G2WMA1, N1P350
      Conserved Domains (2) summary
      cd06174
      Location:81 → 481
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      COG0738
      Location:77 → 497
      FucP; Fucose permease [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08280.1

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