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    ASG1 Asg1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854676, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ASG1
    Official Full Name
    Asg1p
    Primary source
    SGD:S000001392
    Locus tag
    YIL130W
    See related
    AllianceGenome:SGD:S000001392; FungiDB:YIL130W; VEuPathDB:YIL130W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See ASG1 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (102782..105676)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Csm2p Neighboring gene forkhead family transcription factor FKH1 Neighboring gene Tao3p Neighboring gene Met18p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The zinc cluster transcriptional regulator Asg1 transcriptionally coordinates oleate utilization and lipid accumulation in Saccharomyces cerevisiae. Jansuriyakul S, et al. Appl Microbiol Biotechnol, 2016 May. PMID 26875874
    2. A new laboratory evolution approach to select for constitutive acetic acid tolerance in Saccharomyces cerevisiae and identification of causal mutations. González-Ramos D, et al. Biotechnol Biofuels, 2016. PMID 27525042, Free PMC Article
    3. New regulators of drug sensitivity in the family of yeast zinc cluster proteins. Akache B, et al. J Biol Chem, 2002 Jun 14. PMID 11943786
    4. Chromosome-level genome assembly and structural variant analysis of two laboratory yeast strains from the Peterhof Genetic Collection lineage. Barbitoff YA, et al. G3 (Bethesda), 2021 Apr 15. PMID 33677552, Free PMC Article
    5. Life-span extension by pigmented rice bran in the model yeast Saccharomyces cerevisiae. Sunthonkun P, et al. Sci Rep, 2019 Dec 2. PMID 31792269, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results highlight a new role of the transcriptional regulator Asg1 in coordinating expression of genes involved in fatty acid utilization and its role in regulating cellular lipid accumulation.
      Title: The zinc cluster transcriptional regulator Asg1 transcriptionally coordinates oleate utilization and lipid accumulation in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Asg1p
    NP_012136.1
    • Zinc cluster protein proposed to be a transcriptional regulator; regulator involved in the stress response; regulates utilization of fatty acids and accumulation of lipids

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      102782..105676
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179478.1 → NP_012136.1  TPA: Asg1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012136.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVF7, P40467, Q45U13
      UniProtKB/TrEMBL
      B5VKH7
      Conserved Domains (2) summary
      cd12148
      Location:241 → 662
      fungal_TF_MHR; fungal transcription factor regulatory middle homology region
      smart00066
      Location:15 → 56
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40467.1

    Gene LinkOut

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