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    ace2 DNA-binding transcription factor Ace2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541661, updated on 22-Jun-2024

    Summary

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    Gene symbol
    ace2
    Gene description
    DNA-binding transcription factor Ace2
    Locus tag
    SPOM_SPAC6G10.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPAC6G10.12c
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    Genomic context

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    See ace2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3239232..3241153, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-40S ribosomal protein S31 fusion protein Neighboring gene uncharacterized protein Neighboring gene RNA-binding protein Nop9 Neighboring gene ncRNA Neighboring gene histone H3.3 H4 heterotetramer chaperone Rtt106

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription regulation of the alpha-glucanase gene agn1 by cell separation transcription factor Ace2p in fission yeast. Dekker N, et al. FEBS Lett, 2006 May 29. PMID 16678171
    2. Ace2p controls the expression of genes required for cell separation in Schizosaccharomyces pombe. Alonso-Nuñez ML, et al. Mol Biol Cell, 2005 Apr. PMID 15689498, Free PMC Article
    3. Transcription factors mediate condensin recruitment and global chromosomal organization in fission yeast. Kim KD, et al. Nat Genet, 2016 Oct. PMID 27548313, Free PMC Article
    4. The Med8 mediator subunit interacts with the Rpb4 subunit of RNA polymerase II and Ace2 transcriptional activator in Schizosaccharomyces pombe. Mehta S, et al. FEBS Lett, 2009 Oct 6. PMID 19720063
    5. Ace2p contributes to fission yeast septin ring assembly by regulating mid2+ expression. Petit CS, et al. J Cell Sci, 2005 Dec 15. PMID 16317047

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Med8 mediator subunit is involved in transmitting regulatory information from Ace2 to RNA polymerase II via Rpb4.
      Title: The Med8 mediator subunit interacts with the Rpb4 subunit of RNA polymerase II and Ace2 transcriptional activator in Schizosaccharomyces pombe.
    2. identification of seven genes (adg1(+), adg2(+), adg3(+), cfh4(+), agn1(+), eng1(+), and mid2(+)) whose expression is induced by the transcription factor Ace2p
      Title: Ace2p controls the expression of genes required for cell separation in Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    NOT is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-binding transcription factor Ace2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3239232..3241153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019533.3 → NP_594109.1  DNA-binding transcription factor Ace2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594109.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14258
      Conserved Domains (4) summary
      COG5048
      Location:45 → 518
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:448 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:473 → 495
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:487 → 511
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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