U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    UBP16 putative ubiquitin-specific protease UBP16 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856032, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    UBP16
    Official Full Name
    putative ubiquitin-specific protease UBP16
    Primary source
    SGD:S000005993
    Locus tag
    YPL072W
    See related
    AllianceGenome:SGD:S000005993; FungiDB:YPL072W; VEuPathDB:YPL072W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination. Located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See UBP16 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (418512..420011)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene transcription regulator GCR1 Neighboring gene putative AAA family ATPase YTA6 Neighboring gene uncharacterized protein Neighboring gene guanine nucleotide exchange factor MUK1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The yeast deubiquitinating enzyme Ubp16 is anchored to the outer mitochondrial membrane. Kinner A, et al. FEBS Lett, 2003 Aug 14. PMID 12914939
    2. Ubiquitin-dependent protein degradation. Hochstrasser M. Annu Rev Genet, 1996. PMID 8982460
    3. Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae. Amerik AY, et al. Biol Chem, 2000 Sep-Oct. PMID 11076031
    4. Mitochondrial complexome reveals quality-control pathways of protein import. Schulte U, et al. Nature, 2023 Feb. PMID 36697829, Free PMC Article
    5. Genetic interactions of a putative Arabidopsis thaliana ubiquitin-ligase with components of the Saccharomyces cerevisiae ubiquitination machinery. Aguilar-Henonin L, et al. Curr Genet, 2006 Oct. PMID 16897085

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type deubiquitinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein deubiquitination TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane HDA PubMed 
    located_in mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    putative ubiquitin-specific protease UBP16
    NP_015253.1
    • Putative deubiquitinating enzyme anchored to the outer mitochondrial membrane; probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      418512..420011
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183886.1 → NP_015253.1  TPA: putative ubiquitin-specific protease UBP16 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015253.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3U3, Q02863
      UniProtKB/TrEMBL
      A6ZWH7, B3LKZ7, B5VT91, C7GTY5, N1P1P1
      Conserved Domains (1) summary
      cd02662
      Location:54 → 495
      Peptidase_C19F; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q02863.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools